Martian atmospheric compositional analysis- its biological significance first quarterly progress report, 15 may - 15 aug. 1965

Biological significance of Martian atmospheric compositional analysis, and life detection studies of chemical free energy in surface matte

RNA and protein synthesis in Neurospora crassa conidia

RNA and protein synthesis in conidi

Bicycle Safety Supplement to Teacher Buggy Driving Safety Curriculum

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Materiales y tecnologías en la Arquitectura Modernista: casos de estudio de decoración de fachadas en Italia, Portugal y Polonia persiguiendo una restauración racional

The results of a diagnostic survey on the materials of representative Art Nouveau buildings in Italy, Portugal and Poland are here presented and compared, as a contribution to their understanding and, hence, to support compatible restoration. In particular, the facade decorations were investigated for the appraisal of their materials and technologies, often neglected in current maintenance/restoration works and so cancelled, leading to a severe loss in architectural image. The ongoing diagnostic campaign, in collaboration among different universities, is aimed to set up a database on materials and technologies of Art Nouveau facade decorations at a European scale, as a technical-scientific background for the highlighting of preservation guidelines

Progranulin regulates neurogenesis in the developing vertebrate retina

We evaluated the expression and function of the microglia‐specific growth factor, Progranulin‐a (Pgrn‐a) during developmental neurogenesis in the embryonic retina of zebrafish. At 24 hpf pgrn‐a is expressed throughout the forebrain, but by 48 hpf pgrn‐a is exclusively expressed by microglia and/or microglial precursors within the brain and retina. Knockdown of Pgrn‐a does not alter the onset of neurogenic programs or increase cell death, however, in its absence, neurogenesis is significantly delayed—retinal progenitors fail to exit the cell cycle at the appropriate developmental time and postmitotic cells do not acquire markers of terminal differentiation, and microglial precursors do not colonize the retina. Given the link between Progranulin and cell cycle regulation in peripheral tissues and transformed cells, we analyzed cell cycle kinetics among retinal progenitors following Pgrn‐a knockdown. Depleting Pgrn‐a results in a significant lengthening of the cell cycle. These data suggest that Pgrn‐a plays a dual role during nervous system development by governing the rate at which progenitors progress through the cell cycle and attracting microglial progenitors into the embryonic brain and retina. Collectively, these data show that Pgrn‐a governs neurogenesis by regulating cell cycle kinetics and the transition from proliferation to cell cycle exit and differentiation. © 2017 The Authors. Developmental Neurobiology Published by Wiley Periodicals, Inc. Develop Neurobiol 77: 1114–1129, 2017Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138360/1/dneu22499.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138360/2/dneu22499_am.pd

Current Status of Copyright Protection in the Digital Age and Related Topics

This Article provides a basic overview of the recent amendments to the copyright law, including the DMCA and recent developments generally, in relation to the protection of digital works. While portions of the discussion are directed to general copyright law, the primary discussion is directed specifically to legal theories used to protect or defend digital works. Interestingly, the DMCA amendments affect only slightly the rights incident to a copyrighted work, but provide significant protection against unauthorized access to copyrighted works

Effect of cycloheximide and actinomycin D on germinating conidia

Effect of cycloheximide and actinomycin D on germinating conidi

What other STI testing should we do for a patient with chlamydia?

Testing for gonorrhea is recommended for a patient with genital chlamydia; also test for gonorrhea and chlamydia in their sexual partner because of the high prevalence of coinfection, particularly among younger patients (strength of recommendation [SOR]: C, based on expert opinion and observational studies). Testing for syphilis and HIV is also recommended for the patient and their partner (SOR: C, based on expert opinion)

Dual Geometric Worm Algorithm for Two-Dimensional Discrete Classical Lattice Models

We present a dual geometrical worm algorithm for two-dimensional Ising models. The existence of such dual algorithms was first pointed out by Prokof'ev and Svistunov \cite{ProkofevClassical}. The algorithm is defined on the dual lattice and is formulated in terms of bond-variables and can therefore be generalized to other two-dimensional models that can be formulated in terms of bond-variables. We also discuss two related algorithms formulated on the direct lattice, applicable in any dimension. These latter algorithms turn out to be less efficient but of considerable intrinsic interest. We show how such algorithms quite generally can be "directed" by minimizing the probability for the worms to erase themselves. Explicit proofs of detailed balance are given for all the algorithms. In terms of computational efficiency the dual geometrical worm algorithm is comparable to well known cluster algorithms such as the Swendsen-Wang and Wolff algorithms, however, it is quite different in structure and allows for a very simple and efficient implementation. The dual algorithm also allows for a very elegant way of calculating the domain wall free energy.Comment: 12 pages, 6 figures, Revtex